Rapid Molecular Diagnosis of the Mycobacterium Tuberculosis Rangipo Strain Responsible for the Largest Recurring TB Cluster in New Zealand

Diagn Microbiol Infect Dis. 2017 Jun;88(2):138-140. doi: 10.1016/j.diagmicrobio.2017.03.012. Epub 2017 Mar 23.

Abstract

Despite New Zealand being a low-tuberculosis (TB) burden country, there are disproportionately high rates of TB in particular populations. Here, we report a rapid molecular diagnosis of the Mycobacterium tuberculosis Rangipo strain responsible for the largest recurring TB cluster in New Zealand.

Keywords: Diagnostic; Māori; New Zealand; Tuberculosis; Whole-genome sequencing.

MeSH terms

  • Base Sequence
  • Cluster Analysis
  • Genome, Bacterial / genetics
  • Humans
  • Molecular Typing / methods*
  • Mycobacterium tuberculosis / classification*
  • Mycobacterium tuberculosis / genetics*
  • Mycobacterium tuberculosis / isolation & purification
  • New Zealand
  • Polymorphism, Single Nucleotide / genetics
  • Sequence Alignment
  • Tuberculosis, Pulmonary / diagnosis*
  • Tuberculosis, Pulmonary / microbiology