Enhanced Proteolytic Activities in Acral Peeling Skin Syndrome: A Role of Transglutaminase 5 in Epidermal Homeostasis

J Invest Dermatol. 2017 Aug;137(8):1808-1811. doi: 10.1016/j.jid.2017.03.026. Epub 2017 Apr 7.

Authors

Georgios Pampalakis¹, Dimitra Kiritsi², Eleni Zingkou¹, Claus-Werner Franzke², Manthoula Valari³, Georgia Sotiropoulou⁴

Affiliations

¹ Department of Pharmacy, School of Health Sciences, University of Patras, Rion-Patras, Greece.
² Department of Dermatology, Medical Center-University of Freiburg, Freiburg, Germany.
³ Department of Dermatology, Aghia Sofia Children's Hospital, Athens, Greece.
⁴ Department of Pharmacy, School of Health Sciences, University of Patras, Rion-Patras, Greece. Electronic address: gdsotiro@upatras.gr.

PMID: 28395976
DOI: 10.1016/j.jid.2017.03.026

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Epidermis / enzymology*
Epidermis / pathology
Homeostasis
Humans
Proteolysis
Skin Diseases / congenital*
Skin Diseases / metabolism
Skin Diseases / pathology
Transglutaminases / metabolism*

Substances

transglutaminase 5
Transglutaminases

Supplementary concepts

Peeling skin syndrome, acral type