Genetics of hydroxyacid oxidase isozymes in the mouse: localisation of Hao-2 on linkage group XVI

Heredity (Edinb). 1978 Dec;41(3):403-6. doi: 10.1038/hdy.1978.111.


Electrophoretic variants of individual isozymes of L-alpha-hydroxyacid oxidase (HAOX-B4) and amylase (AMY-A) in an Asian subspecies of mouse, Mus musculus castaneus, have been used to localise the gene encoding the HAOX B subunit. The structural gene loci for these isozymes (Hao-2 and Amy-1) are apparently linked (4.9 +/- 2.4 per cent recombinants) in this organism, which places Hao-2 on linkage group XVI, since previous studies by Eicher and co-workers (1976) have localised Amy-1 on this chromosome.

MeSH terms

  • Alcohol Oxidoreductases / genetics*
  • Amylases / genetics*
  • Animals
  • Chromosome Mapping
  • Crosses, Genetic
  • Female
  • Genes*
  • Genetic Linkage
  • Isoenzymes / genetics*
  • Male
  • Mice
  • Mice, Inbred C57BL


  • Isoenzymes
  • Alcohol Oxidoreductases
  • Amylases