Arnica montana L. - a plant of healing: review

J Pharm Pharmacol. 2017 Aug;69(8):925-945. doi: 10.1111/jphp.12724. Epub 2017 Apr 11.

Abstract

Objectives: Arnica montana is a widely used therapeutic plant used traditionally to treat various ailments. The objective of this study was to evaluate the botany, phytochemistry and ethnopharmacology along with special emphasis given on pharmacological activity of plant A. montana.

Key findings: The plant extracts have been reported to possess antibacterial, antitumor, antioxidant, anti-inflammatory, antifungal and immunomodulatory activity. A wide range of chemical compounds including sesquiterpene lactones and their short-chain carbonic acid esters, flavonoids, carotenoids, essential oils, diterpenes, arnidiol, pyrrolizidine alkaloids, coumarins, phenolic acids, lignans and oligosaccharides, etc., are found in different parts of the plant.

Summary: It has been scrutinized that extensive research has been carried out to explore the therapeutic potential of flowers of the plant. Therefore, investigations should be carried out to explore the therapeutic potential of other parts of the plant for better therapeutic utilization.

Keywords: Arnica montana; anti-inflammatory; helenalin; sesquiterpene lactones.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / isolation & purification
  • Anti-Inflammatory Agents / pharmacology
  • Anti-Inflammatory Agents / therapeutic use*
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology
  • Antioxidants / therapeutic use*
  • Arnica*
  • Ethnopharmacology / methods
  • Ethnopharmacology / trends
  • Flowers
  • Humans
  • Inflammation / drug therapy
  • Inflammation / metabolism
  • Phytotherapy / methods*
  • Phytotherapy / trends
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use*
  • Plant Roots
  • Seeds
  • Wound Healing / drug effects
  • Wound Healing / physiology

Substances

  • Anti-Inflammatory Agents
  • Antioxidants
  • Plant Extracts