Mantle Cell Lymphoma: Contemporary Diagnostic and Treatment Perspectives in the Age of Personalized Medicine

Hematol Oncol Stem Cell Ther. 2017 Sep;10(3):99-115. doi: 10.1016/j.hemonc.2017.02.003. Epub 2017 Apr 6.


Mantle cell lymphoma is a clinically heterogeneous disease occurring within a heterogeneous patient population, highlighting a need for personalized therapy to ensure optimal outcomes. It is therefore critical to understand the benefits and risks associated with both intensive and deintensified approaches. In the following review we provide a therapeutic roadmap to strategically guide treatment for newly diagnosed and relapsed/refractory patients highlighting pivotal and recently published results involving known and novel therapies.

Keywords: Mantle cell lymphoma; Prognosis; Treatment.

Publication types

  • Review

MeSH terms

  • Humans
  • Lymphoma, Mantle-Cell / diagnosis*
  • Lymphoma, Mantle-Cell / therapy*
  • Precision Medicine
  • Prognosis