Haemorrhagic cholecystitis in a newly anticoagulated patient

BMJ Case Rep. 2017 Apr 12:2017:bcr2016214617. doi: 10.1136/bcr-2016-214617.

Abstract

A 74-year-old man undergoing rehabilitation after pneumonia developed right upper quadrant abdominal pain. Five days earlier he had been commenced on apixaban for a new diagnosis of atrial fibrillation. Ultrasound and CT scans revealed an acalculous grossly thickened gallbladder, with high attenuation non-echogenic material both within and surrounding the structure. Active contrast extravasation was seen at the neck. On laparotomy, a perforated internally bleeding gallbladder containing a single calculus was found, with significant free blood within the abdomen. After cholecystectomy, the patient recovered slowly in hospital before nursing home placement.

Keywords: Drugs and medicines; Gastrointestinal surgery; Haematology; Surgery.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cholecystitis / chemically induced
  • Cholecystitis / diagnostic imaging*
  • Cholecystitis / surgery
  • Gastrointestinal Hemorrhage / etiology*
  • Humans
  • Male
  • Pyrazoles / administration & dosage*
  • Pyrazoles / adverse effects
  • Pyridones / administration & dosage*
  • Pyridones / adverse effects
  • Treatment Outcome

Substances

  • Pyrazoles
  • Pyridones
  • apixaban