The interpretation of mu suppression as an index of mirror neuron activity: past, present and future

R Soc Open Sci. 2017 Mar 1;4(3):160662. doi: 10.1098/rsos.160662. eCollection 2017 Mar.

Abstract

Mu suppression studies have been widely used to infer the activity of the human mirror neuron system (MNS) in a number of processes, ranging from action understanding, language, empathy and the development of autism spectrum disorders (ASDs). Although mu suppression is enjoying a resurgence of interest, it has a long history. This review aimed to revisit mu's past, and examine its recent use to investigate MNS involvement in language, social processes and ASDs. Mu suppression studies have largely failed to produce robust evidence for the role of the MNS in these domains. Several key potential shortcomings with the use and interpretation of mu suppression, documented in the older literature and highlighted by more recent reports, are explored here.

Keywords: alpha rhythm; electroencephalogram; mirror neurons; mu rhythm.

Publication types

  • Review