Water-soluble chitosan inhibits nerve growth factor and attenuates allergic inflammation in mite allergen-induced allergic rhinitis

J Allergy Clin Immunol. 2017 Oct;140(4):1146-1149.e8. doi: 10.1016/j.jaci.2017.03.022. Epub 2017 Apr 12.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Intranasal
  • Allergens / immunology
  • Animals
  • Antigens, Dermatophagoides / immunology
  • Arthropod Proteins / immunology
  • Cell Line
  • Chitosan / administration & dosage*
  • Chitosan / chemistry
  • Cysteine Endopeptidases / immunology
  • Female
  • Immunoglobulin E / blood
  • Mice, Inbred BALB C
  • Mice, Inbred C57BL
  • Mice, Transgenic
  • Mites / immunology
  • Nasal Mucosa / drug effects
  • Nasal Mucosa / pathology
  • Nerve Growth Factor / antagonists & inhibitors*
  • Nerve Growth Factor / genetics
  • Nerve Growth Factor / immunology
  • Rhinitis, Allergic / drug therapy*
  • Rhinitis, Allergic / immunology
  • Rhinitis, Allergic / pathology
  • Water

Substances

  • Allergens
  • Antigens, Dermatophagoides
  • Arthropod Proteins
  • Water
  • Immunoglobulin E
  • Chitosan
  • Nerve Growth Factor
  • Cysteine Endopeptidases
  • Dermatophagoides pteronyssinus antigen p 1