Hepatic inflammatory pseudotumour-like follicular dendritic cell tumor: A case report

Mol Clin Oncol. 2017 Apr;6(4):547-549. doi: 10.3892/mco.2017.1188. Epub 2017 Mar 8.

Abstract

Hepatic inflammatory pseudotumor (IPT)-like follicular dendritic cell (FDC) tumor is a rare neoplasm. We herein report the case of 19-year-old female patient with an IPT-like FDC tumor and summarize 24 cases of hepatic FDC tumors previously reported in the English literature. The patient presented with complaints of abdominal discomfort, without significant laboratory abnormalities, and underwent surgical removal of a hepatic tumor. The resected tumor was 6 cm in the longest diameter and the tumor cells were positive for CD21, CD35 and Epstein-Barr virus (EBV). The postoperative course was uneventful and there have been no metastases or recurrence during 1 year of follow-up. The majority of the cases of hepatic IPT-like FDC tumors have a female predominance and exhibit an association with EBV infection. Their clinical manifestations and image findings are usually non-specific and the diagnosis of this disease mainly relies on pathology.

Keywords: CD21; Ebstein Barr virus; follicular dendritic cell tumor; hepatic neoplasms; inflammatory pseudotumour.