Sequential sensory and decision processing in posterior parietal cortex

Elife. 2017 Apr 24;6:e23743. doi: 10.7554/eLife.23743.

Abstract

Decisions about the behavioral significance of sensory stimuli often require comparing sensory inference of what we are looking at to internal models of what we are looking for. Here, we test how neuronal selectivity for visual features is transformed into decision-related signals in posterior parietal cortex (area LIP). Monkeys performed a visual matching task that required them to detect target stimuli composed of conjunctions of color and motion-direction. Neuronal recordings from area LIP revealed two main findings. First, the sequential processing of visual features and the selection of target-stimuli suggest that LIP is involved in transforming sensory information into decision-related signals. Second, the patterns of color and motion selectivity and their impact on decision-related encoding suggest that LIP plays a role in detecting target stimuli by comparing bottom-up sensory inputs (what the monkeys were looking at) and top-down cognitive encoding inputs (what the monkeys were looking for).

Keywords: Parietal Cortex; Prefrontal Cortex; attention; decision making; neuroscience; rhesus macaque; vision; visual perception.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Decision Making*
  • Electroencephalography
  • Macaca mulatta
  • Motion Perception*
  • Parietal Lobe / physiology*
  • Visual Perception*