β-Blocker Exposure in Pregnancy and Risk of Fetal Cardiac Anomalies

doi:10.1001/jamainternmed.2017.0608

. 2017 Jun 1;177(6):885-887.

doi: 10.1001/jamainternmed.2017.0608.

β-Blocker Exposure in Pregnancy and Risk of Fetal Cardiac Anomalies

Lewei Duan¹, Angie Ng², Wansu Chen¹, Hillard T Spencer³, Jennifer Nguyen², Albert Y-J Shen², Ming-Sum Lee²

Affiliations

¹ Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California.
² Division of Cardiology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California.
³ Southern California Permanente Medical Group, Los Angeles, California.

PMID: 28418448
PMCID: PMC5818837
DOI: 10.1001/jamainternmed.2017.0608

β-Blocker Exposure in Pregnancy and Risk of Fetal Cardiac Anomalies

Lewei Duan et al. JAMA Intern Med. 2017.

. 2017 Jun 1;177(6):885-887.

doi: 10.1001/jamainternmed.2017.0608.

Authors

Lewei Duan¹, Angie Ng², Wansu Chen¹, Hillard T Spencer³, Jennifer Nguyen², Albert Y-J Shen², Ming-Sum Lee²

Affiliations

¹ Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California.
² Division of Cardiology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California.
³ Southern California Permanente Medical Group, Los Angeles, California.

PMID: 28418448
PMCID: PMC5818837
DOI: 10.1001/jamainternmed.2017.0608

Abstract

This population-based cohort study examines the risk of fetal cardiac malformations associated with maternal β-blocker exposure.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures: None reported.

Comment in

Maternal β-Blocker Use and Fetal Cardiac Anomalies.
Keskin-Arslan E, Akoz A, Kaplan YC. Keskin-Arslan E, et al. JAMA Intern Med. 2017 Nov 1;177(11):1692. doi: 10.1001/jamainternmed.2017.4894. JAMA Intern Med. 2017. PMID: 29114787 No abstract available.
Maternal β-Blocker Use and Fetal Cardiac Anomalies-Reply.
Lee MS, Duan L. Lee MS, et al. JAMA Intern Med. 2017 Nov 1;177(11):1692-1693. doi: 10.1001/jamainternmed.2017.4900. JAMA Intern Med. 2017. PMID: 29114796 No abstract available.

Cited by

What Do We Know about Peripartum Cardiomyopathy? Yesterday, Today, Tomorrow.
Lasica R, Asanin M, Vukmirovic J, Maslac L, Savic L, Zdravkovic M, Simeunovic D, Polovina M, Milosevic A, Matic D, Juricic S, Jankovic M, Marinkovic M, Djukanovic L. Lasica R, et al. Int J Mol Sci. 2024 Sep 30;25(19):10559. doi: 10.3390/ijms251910559. Int J Mol Sci. 2024. PMID: 39408885 Free PMC article. Review.
Antiarrhythmic Drug Use in Pregnancy: Considerations and Safety Profiles.
Mariani MV, Pierucci N, La Fazia VM, Cipollone P, Micillo M, D'Amato A, Fanisio F, Ammirati G, Salagundla N, Lavalle C, Perrone MA. Mariani MV, et al. J Cardiovasc Dev Dis. 2024 Aug 7;11(8):243. doi: 10.3390/jcdd11080243. J Cardiovasc Dev Dis. 2024. PMID: 39195151 Free PMC article. Review.
Genetic Insights Into Perinatal Outcomes of Maternal Antihypertensive Therapy During Pregnancy.
Barry CS, Walker VM, Burden C, Havdahl A, Davies NM. Barry CS, et al. JAMA Netw Open. 2024 Aug 1;7(8):e2426234. doi: 10.1001/jamanetworkopen.2024.26234. JAMA Netw Open. 2024. PMID: 39190310 Free PMC article.
Management of cardiac emergencies in women: a clinical consensus statement of the Association for Acute CardioVascular Care (ACVC), the European Association of Percutaneous Cardiovascular Interventions (EAPCI), the Heart Failure Association (HFA), and the European Heart Rhythm Association (EHRA) of the ESC, and the ESC Working Group on Cardiovascular Pharmacotherapy.
Sambola A, Halvorsen S, Adlam D, Hassager C, Price S, Rosano G, Schiele F, Holmvang L, de Riva M, Rakisheva A, Sulzgruber P, Swahn E. Sambola A, et al. Eur Heart J Open. 2024 Feb 26;4(2):oeae011. doi: 10.1093/ehjopen/oeae011. eCollection 2024 Mar. Eur Heart J Open. 2024. PMID: 38628674 Free PMC article. Review.
Beta-Blockers and Their Current Role in Maternal and Neonatal Health: A Narrative Review of the Literature.
Martinez A, Lakkimsetti M, Maharjan S, Aslam MA, Basnyat A, Kafley S, Reddy SS, Ahmed SS, Razzaq W, Adusumilli S, Khawaja UA. Martinez A, et al. Cureus. 2023 Aug 24;15(8):e44043. doi: 10.7759/cureus.44043. eCollection 2023 Aug. Cureus. 2023. PMID: 37746367 Free PMC article. Review.

See all "Cited by" articles

References

1. Ruys TP, Maggioni A, Johnson MR, et al. . Cardiac medication during pregnancy, data from the ROPAC. Int J Cardiol. 2014;177(1):124-128. - PubMed
1. Davis RL, Eastman D, McPhillips H, et al. . Risks of congenital malformations and perinatal events among infants exposed to calcium channel and beta-blockers during pregnancy. Pharmacoepidemiol Drug Saf. 2011;20(2):138-145. - PMC - PubMed
1. Bateman BT, Patorno E, Desai RJ, et al. . Late pregnancy β blocker exposure and risks of neonatal hypoglycemia and bradycardia. Pediatrics. 2016;138(3):e20160731. - PMC - PubMed
1. Yakoob MY, Bateman BT, Ho E, et al. . The risk of congenital malformations associated with exposure to β-blockers early in pregnancy: a meta-analysis. Hypertension. 2013;62(2):375-381. - PMC - PubMed

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
Other Literature Sources
- scite Smart Citations
Medical
- MedlinePlus Health Information

[1] Ruys TP, Maggioni A, Johnson MR, et al. . Cardiac medication during pregnancy, data from the ROPAC. Int J Cardiol. 2014;177(1):124-128. - PubMed

[2] Ruys TP, Maggioni A, Johnson MR, et al. . Cardiac medication during pregnancy, data from the ROPAC. Int J Cardiol. 2014;177(1):124-128. - PubMed

[3] Davis RL, Eastman D, McPhillips H, et al. . Risks of congenital malformations and perinatal events among infants exposed to calcium channel and beta-blockers during pregnancy. Pharmacoepidemiol Drug Saf. 2011;20(2):138-145. - PMC - PubMed

[4] Davis RL, Eastman D, McPhillips H, et al. . Risks of congenital malformations and perinatal events among infants exposed to calcium channel and beta-blockers during pregnancy. Pharmacoepidemiol Drug Saf. 2011;20(2):138-145. - PMC - PubMed

[5] Bateman BT, Patorno E, Desai RJ, et al. . Late pregnancy β blocker exposure and risks of neonatal hypoglycemia and bradycardia. Pediatrics. 2016;138(3):e20160731. - PMC - PubMed

[6] Bateman BT, Patorno E, Desai RJ, et al. . Late pregnancy β blocker exposure and risks of neonatal hypoglycemia and bradycardia. Pediatrics. 2016;138(3):e20160731. - PMC - PubMed

[7] Yakoob MY, Bateman BT, Ho E, et al. . The risk of congenital malformations associated with exposure to β-blockers early in pregnancy: a meta-analysis. Hypertension. 2013;62(2):375-381. - PMC - PubMed

[8] Yakoob MY, Bateman BT, Ho E, et al. . The risk of congenital malformations associated with exposure to β-blockers early in pregnancy: a meta-analysis. Hypertension. 2013;62(2):375-381. - PMC - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

β-Blocker Exposure in Pregnancy and Risk of Fetal Cardiac Anomalies

Affiliations

β-Blocker Exposure in Pregnancy and Risk of Fetal Cardiac Anomalies

Authors

Affiliations

Abstract

Conflict of interest statement

Comment in

Similar articles

Cited by

References

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Abstract

Conflict of interest statement

Comment in

Similar articles

Cited by

References

MeSH terms

Substances

Related information

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical