The aim of the study was to investigate femoral neck strain during maximal isometric contraction of the hip-spanning muscles. The musculoskeletal and the femur finite-element models from an elderly white woman were taken from earlier studies. The hip-spanning muscles were grouped by function in six hip-spanning muscle groups. The peak hip and knee moments in the model were matched to corresponding published measurements of the hip and knee moments during maximal isometric exercises about the hip and the knee in elderly participants. The femoral neck strain was calculated using full activation of the agonist muscles at fourteen physiological joint angles. The 5% ± 0.8% of the femoral neck volume exceeded the 90th percentile of the strain distribution across the 84 studied scenarios. Hip extensors, flexors, and abductors generated the highest tension in the proximal neck (2727 με), tension (986 με) and compression (-2818 με) in the anterior and posterior neck, and compression (-2069 με) in the distal neck, respectively. Hip extensors and flexors generated the highest neck strain per unit of joint moment (63-67 με·m·N-1) at extreme hip angles. Therefore, femoral neck strain is heterogeneous and muscle contraction and posture dependent.