Abstract
The level of gene expression and the protein content of tyrosine hydroxylase and dopamine β-hydroxylase were determined. In the perinatal period of rats, when noradrenaline functions as a morphogenetic factor, the level of gene expression of these enzymes increased and the content of protein products of these genes was almost unchanged, indicating the difference in the regulatory mechanisms of their transcription and translation.
MeSH terms
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Adrenal Glands / embryology
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Adrenal Glands / enzymology
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Adrenal Glands / metabolism*
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Animals
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Dopamine beta-Hydroxylase / genetics
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Dopamine beta-Hydroxylase / metabolism
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Gene Expression Regulation, Developmental*
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Male
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Norepinephrine / metabolism*
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Organogenesis
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RNA, Messenger / genetics
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RNA, Messenger / metabolism
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Rats
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Rats, Wistar
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Tyrosine 3-Monooxygenase / genetics
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Tyrosine 3-Monooxygenase / metabolism
Substances
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RNA, Messenger
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Tyrosine 3-Monooxygenase
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Dopamine beta-Hydroxylase
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Norepinephrine