Discrimination between ulcerative colitis and Crohn's disease using phage display identified peptides and virus-mimicking synthetic nanoparticles

Sonia Facchin; Liboria Digiglio; Renata D'Incà; Elisabetta Casarin; Elisa Dassie; Monica Dettin; Annj Zamuner; Andrea Buda; Michele De Boni; Duilio Della Libera; Alessandra D'Urso; Giacomo Carlo Sturniolo; Margherita Morpurgo

doi:10.1016/j.nano.2017.04.007

Discrimination between ulcerative colitis and Crohn's disease using phage display identified peptides and virus-mimicking synthetic nanoparticles

Nanomedicine. 2017 Aug;13(6):2027-2036. doi: 10.1016/j.nano.2017.04.007. Epub 2017 Apr 18.

Authors

Affiliations

¹ Department of Surgery, Oncology and Gastroenterology, Gastroenterology Section, University Hospital of Padua, Padua, Italy. Electronic address: sonia.facchin@unipd.it.
² Department of Surgery, Oncology and Gastroenterology, Gastroenterology Section, University Hospital of Padua, Padua, Italy. Electronic address: l.digiglio@alice.it.
³ Department of Surgery, Oncology and Gastroenterology, Gastroenterology Section, University Hospital of Padua, Padua, Italy. Electronic address: dinca@unipd.it.
⁴ Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy. Electronic address: elisabetta.casarin.81@gmail.com.
⁵ Department of Molecular Medicine, University of Padua, Padua, Italy; Department of Industrial Engineering, University of Padua, Padua, Italy; Oncological Gastrointestinal Surgery Department, S. Maria del Prato Hospital, Feltre, Italy; Venetian Institute of Molecular Medicine, Padua, Italy. Electronic address: elisa.dassie@ymail.com.
⁶ Department of Industrial Engineering, University of Padua, Padua, Italy. Electronic address: monica.dettin@unipd.it.
⁷ Department of Industrial Engineering, University of Padua, Padua, Italy. Electronic address: annj.zamuner@phd.unipd.it.
⁸ Oncological Gastrointestinal Surgery Department, S. Maria del Prato Hospital, Feltre, Italy. Electronic address: andrea.buda@unipd.it.
⁹ Oncological Gastrointestinal Surgery Department, S. Maria del Prato Hospital, Feltre, Italy. Electronic address: debonimichele24@gmail.com.
¹⁰ Oncological Gastrointestinal Surgery Department, S. Maria del Prato Hospital, Feltre, Italy. Electronic address: dudellal@tin.it.
¹¹ Oncological Gastrointestinal Surgery Department, S. Maria del Prato Hospital, Feltre, Italy. Electronic address: ale_durso@inwind.it.
¹² Department of Surgery, Oncology and Gastroenterology, Gastroenterology Section, University Hospital of Padua, Padua, Italy. Electronic address: gc.sturniolo@unipd.it.
¹³ Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy. Electronic address: margherita.morpurgo@unipd.it.

PMID: 28428053
DOI: 10.1016/j.nano.2017.04.007

No abstract available

Keywords: ANANAS; Biomarker; Diagnosis; IBD; Phage display.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacteriophages / chemistry*
Bacteriophages / metabolism
Biomimetic Materials / administration & dosage*
Biomimetic Materials / chemistry
Colitis, Ulcerative / diagnosis*
Colitis, Ulcerative / metabolism
Crohn Disease / diagnosis*
Crohn Disease / metabolism
Drug Delivery Systems*
Humans
Nanoparticles / administration & dosage*
Nanoparticles / chemistry
Peptide Library*

Substances

Peptide Library