Can Type 1 diabetes progression be halted? Possible role of high dose vitamin D and omega 3 fatty acids

Eur Rev Med Pharmacol Sci. 2017 Apr;21(7):1604-1609.

Abstract

In Type 1 Diabetes (T1D) in children, close to the onset the requirements of insulin are often reduced. This represents a transient recovery of endogenous insulin secretion named "honeymoon" because transient and followed by a progressive decline in C-peptide secretion. This case report describes the effect of administration of high dose vitamin D and Ω-3 fatty acids on T1D progression in a 8-year-old child. At today after one year and a half from the onset of T1D, the subject shows a near-normal blood glucose with the administration of 1.5-2 UI of insulin once a day. Thus this report may be of assistance to design additional studies to determine and validate the effect of administration of vitamin D and Ω-3 fatty acids on the progression of T1D.

Publication types

  • Case Reports

MeSH terms

  • Blood Glucose
  • Child
  • Diabetes Mellitus, Type 1 / blood
  • Diabetes Mellitus, Type 1 / physiopathology
  • Diabetes Mellitus, Type 1 / therapy*
  • Disease Progression
  • Fatty Acids, Omega-3 / administration & dosage*
  • Humans
  • Insulin / blood
  • Male
  • Vitamin D / administration & dosage*

Substances

  • Blood Glucose
  • Fatty Acids, Omega-3
  • Insulin
  • Vitamin D