Re-Evaluation of Serum Ferritin Cut-Off Values for the Diagnosis of Iron Deficiency in Children Aged 12-36 Months

J Pediatr. 2017 Sep;188:287-290. doi: 10.1016/j.jpeds.2017.03.028. Epub 2017 Apr 18.


An ongoing challenge has been determining clinically relevant serum ferritin cut-offs in the diagnosis of iron deficiency in children aged 1-3 years. We identified 2 potential clinically relevant serum ferritin cut-off values through their association with clinically important cut-off of hemoglobin as the indicator of anemia.

Keywords: clinically relevant cut-off values; hemoglobin; iron deficiency; preschool children; restricted cubic spline regression; serum ferritin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anemia, Iron-Deficiency / diagnosis*
  • Child, Preschool
  • Cross-Sectional Studies
  • Female
  • Ferritins / blood*
  • Hemoglobins / analysis
  • Humans
  • Infant
  • Male
  • Reference Values
  • Regression Analysis


  • Hemoglobins
  • Ferritins