Wilms tumor and the VATER association

J Urol. 1988 Oct;140(4):787-9. doi: 10.1016/s0022-5347(17)41813-1.


We describe an infant with the VATER association in whom a Wilms tumor was noted when she was 5 months old. The lower pole tumor arose near the pelvis and grew into an adjacent calix producing a cystic and solid mass with numerous papillary projections resembling sarcoma botryoides. Histopathologically, the tumor was a classical Wilms tumor but it was unusual in that the papillary projections of the tumor were covered by intestinal-like epithelium, which was interpreted as metaplastic urothelium. The margins were free of tumor and the patient is being treated according to the National Wilms Tumor Study Protocol for stage I lesions. She is currently without evidence of recurrence.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Multiple / pathology*
  • Anus, Imperforate / pathology
  • Esophagus / abnormalities
  • Female
  • Humans
  • Infant, Newborn
  • Spine / abnormalities
  • Wilms Tumor / pathology*