Laser Endopyelotomy in the Management of Pelviureteric Junction Obstruction in Adults: A Systematic Review of the Literature

Urology. 2017 Sep;107:11-22. doi: 10.1016/j.urology.2017.04.018. Epub 2017 Apr 21.


Laser endopyelotomy (LEP) is considered as an option for the treatment of pelviureteric junction obstruction in adults. A comprehensive systematic search of the published literature was performed to assess the success rate and perioperative complications of LEP in the treatment of primary and secondary pelviureteric junction obstruction and to identify the factors that may have an impact on the success of LEP. The evidence available has significant limitations in terms of the heterogeneous study design and the definitions of outcomes. The average overall success rate of the pooled data was 75% with a mean follow-up of 29 months. Complications were predominately minor with an average rate of 12.5%.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Adult
  • Disease Management*
  • Humans
  • Hydronephrosis / complications
  • Hydronephrosis / congenital*
  • Hydronephrosis / diagnosis
  • Hydronephrosis / surgery
  • Kidney Pelvis / surgery*
  • Laser Therapy / methods*
  • Multicystic Dysplastic Kidney / complications*
  • Multicystic Dysplastic Kidney / diagnosis
  • Multicystic Dysplastic Kidney / surgery
  • Ureteral Obstruction / complications
  • Ureteral Obstruction / diagnosis
  • Ureteral Obstruction / etiology
  • Ureteral Obstruction / surgery*

Supplementary concepts

  • Multicystic renal dysplasia, bilateral