Recommended vitamin D levels in the general population

Endocrinol Diabetes Nutr. 2017 Mar;64 Suppl 1:7-14. doi: 10.1016/j.endinu.2016.11.002. Epub 2017 Feb 15.
[Article in English, Spanish]


Objective: To provide recommendations based on evidence on the management of vitaminD deficiency in the general population.

Participants: Members of the Bone Metabolism Working Group of the Spanish Society of Endocrinology.

Methods: Recommendations were formulated using the GRADE system (Grading of Recommendations, Assessment, Development, and Evaluation) to describe both the strength of recommendations and the quality of evidence. A systematic search was made in MEDLINE (Pubmed) using the term VitaminD and the name of each issue. Papers in English and Spanish with publication date before 17 March 2016 were included. Recommendations were jointly discussed by the Working Group.

Conclusions: This document summarizes the data about vitaminD deficiency in terms of prevalence, etiology, screening indications, adequate levels and effects of supplementation on bone and non-skeletal health outcomes.

Keywords: 25-hidroxivitamina D; 25-hydroxyvitamin D; Calcidiol; Calcitriol; Cancer; Cardiovascular diseases; Caídas; Cholecalciferol; Colecalciferol; Cáncer; Embarazo; Enfermedad cardiovascular; Ergocalciferol; Falls; Fracturas; Fractures; Fuerza muscular; Mortalidad; Mortality; Muscle strength; Osteoporosis; Pregnancy; Vitamin D; Vitamina D.

Publication types

  • Practice Guideline

MeSH terms

  • Accidental Falls / prevention & control
  • Aged
  • Bone Diseases / complications
  • Dietary Supplements
  • Evidence-Based Medicine
  • Female
  • Fractures, Bone / prevention & control
  • Humans
  • Kidney Diseases / complications
  • Liver Diseases / complications
  • Malabsorption Syndromes / complications
  • Male
  • Meta-Analysis as Topic
  • Middle Aged
  • Muscle Weakness / etiology
  • Muscle Weakness / prevention & control
  • Nutritional Requirements
  • Obesity / complications
  • Osteoporosis / prevention & control
  • Risk Factors
  • Vitamin D Deficiency / etiology
  • Vitamin D Deficiency / prevention & control
  • Vitamin D Deficiency / therapy
  • Vitamin D* / analogs & derivatives
  • Vitamin D* / blood


  • Vitamin D
  • 25-hydroxyvitamin D