[The first clinical description of granulomatosis with polyangiitis (known before as Wegener's granulomatosis)]

Rev Med Inst Mex Seguro Soc. 2017 May-Jun;55(3):380-381.
[Article in Spanish]


Before 1950, cases of necrotizing vasculitis were commonly published in journals of pathology. Most of these cases were designated as polyarteritis nodosa. In 1952, the pathologist Pearl Zeek critically reviewed and summarized the literature dealing with polyarteritis nodosa and first grouped the different types of necrotizing vasculitis. But she omitted some types of not well-characterized vasculitis, among them granulomatosis with polyangiitis (Wegener's granulomatosis).

Antes de 1950, los casos de vasculitis necrosantes comúnmente se publicaban en revistas de patología. La mayoría de los casos se designaban poliarteritis nodosa. En 1952, la patóloga Pearl Zeek revisó críticamente la literatura sobre poliarteritis nodosa y por primera vez agrupó los diferentes tipos de vasculitis necrosantes. Sin embargo, omitió algunos tipos de vasculitis, hasta entonces no bien caracterizadas, entre las cuales estaba la granulomatosis con poliangeítis (antes granulomatosis de Wegener).

Keywords: Rheumatoid vasculitis; Wegener’s granulomatosis.

Publication types

  • Historical Article

MeSH terms

  • Germany
  • Granulomatosis with Polyangiitis / diagnosis
  • Granulomatosis with Polyangiitis / history*
  • History, 20th Century
  • Humans
  • New York