Stabilizing the Mixed Lineage Leukemia Protein

N Engl J Med. 2017 Apr 27;376(17):1688-1689. doi: 10.1056/NEJMcibr1700964.
No abstract available

MeSH terms

  • Gene Rearrangement
  • Humans
  • Interleukin-1 / metabolism*
  • Interleukin-1 Receptor-Associated Kinases / antagonists & inhibitors*
  • Interleukin-1 Receptor-Associated Kinases / metabolism
  • Leukemia, Myeloid, Acute / therapy*
  • Myeloid-Lymphoid Leukemia Protein* / genetics
  • Myeloid-Lymphoid Leukemia Protein* / metabolism
  • Oncogene Proteins, Fusion
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy*
  • Receptors, Interleukin-1 / antagonists & inhibitors
  • Receptors, Interleukin-1 / metabolism
  • Transcription, Genetic
  • Translocation, Genetic

Substances

  • Interleukin-1
  • Oncogene Proteins, Fusion
  • Receptors, Interleukin-1
  • Myeloid-Lymphoid Leukemia Protein
  • Interleukin-1 Receptor-Associated Kinases