The Microbiota: A New Variable Impacting Cancer Treatment Outcomes

Clin Cancer Res. 2017 Jul 1;23(13):3229-3231. doi: 10.1158/1078-0432.CCR-17-0864. Epub 2017 Apr 26.

Abstract

Preclinical evidence has established that the host commensal microbiota can contribute to therapeutic response in cancer models, a finding supported by early clinical data. This connection between the microbiome and clinical outcome in oncology is cause for new consideration in the administration of antibiotics and microbiota-modulating interventions to improve outcomes. Clin Cancer Res; 23(13); 3229-31. ©2017 AACRSee related article by Galloway-Peña et al., p. 3263.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Anti-Bacterial Agents / adverse effects
  • Anti-Bacterial Agents / therapeutic use*
  • Humans
  • Microbiota / drug effects*
  • Neoplasms / drug therapy*
  • Neoplasms / microbiology
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents