Preliminary Evidence on Cannabis Effectiveness and Tolerability for Adults With Tourette Syndrome

J Neuropsychiatry Clin Neurosci. Fall 2017;29(4):391-400. doi: 10.1176/appi.neuropsych.16110310. Epub 2017 May 3.

Abstract

The authors retrospectively evaluated effectiveness and tolerability of cannabis in 19 adults with Tourette syndrome. Tics scores decreased by 60%, and 18 of the 19 participants were at least "much improved." Cannabis was generally well tolerated, although most participants reported side effects.

Keywords: Basal Ganglia Disorders; Drug/Psychotherapy Treatment of Neuropsychiatric Disorders; Neuropharmacology; Outcome Studies Biological/Pharmacological.

MeSH terms

  • Adolescent
  • Adult
  • Cannabis / adverse effects
  • Comorbidity
  • Female
  • Humans
  • Male
  • Medical Marijuana* / adverse effects
  • Middle Aged
  • Phytotherapy / adverse effects
  • Preliminary Data
  • Retrospective Studies
  • Severity of Illness Index
  • Tics / drug therapy
  • Tourette Syndrome / drug therapy*
  • Treatment Outcome
  • Young Adult

Substances

  • Medical Marijuana