GGPS1 Mutation and Atypical Femoral Fractures with Bisphosphonates

N Engl J Med. 2017 May 4;376(18):1794-1795. doi: 10.1056/NEJMc1612804.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Amino Acid Sequence
  • Bone Density Conservation Agents / adverse effects*
  • Dimethylallyltranstransferase / genetics*
  • Diphosphonates / adverse effects*
  • Exome
  • Farnesyltranstransferase / genetics*
  • Female
  • Femoral Fractures / chemically induced
  • Femoral Fractures / genetics*
  • Geranyltranstransferase / genetics*
  • Humans
  • Middle Aged
  • Mutation

Substances

  • Bone Density Conservation Agents
  • Diphosphonates
  • Dimethylallyltranstransferase
  • Geranyltranstransferase
  • Farnesyltranstransferase
  • GGPS1 protein, human