Scleroderma Mimickers

Curr Treatm Opt Rheumatol. 2016 Mar;2(1):69-84. doi: 10.1007/s40674-016-0038-7. Epub 2016 Feb 5.


Cutaneous fibrosing disorders encompass a diverse array of diseases united by the presence of varying degrees of dermal sclerosis. The quality and distribution of skin involvement, presence or absence of systemic complications and unique associated laboratory abnormalities often help to distinguish between these diseases. It is imperative that an effort is made to accurately differentiate between scleroderma and its mimics, in order to guide long-term management and facilitate implementation of the appropriate treatment modality where indicated.

Keywords: Eosinophilic fasciitis; Morphea; Nephrogenic systemic fibrosis; Scleredema; Scleroderma; Scleromyxedema; Systemic sclerosis.