Extramammary Paget's disease of the oral mucosa with in situ carcinoma of minor salivary gland ducts

Am J Surg Pathol. 1988 Nov;12(11):890-5. doi: 10.1097/00000478-198811000-00010.


This paper describes a case of oral extramammary Paget's disease associated with widespread in situ carcinoma of minor salivary gland ducts and invasive, poorly differentiated carcinoma. Clinically, the case was characterized by unusually extensive and rapidly spreading erythroplakia of the oral mucosa, accompanied by a relatively small invasive salivary gland carcinoma. Despite the similarities of breast and salivary tissue, oral extramammary Paget's disease appears to be extremely rare.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma in Situ / pathology*
  • Diagnosis, Differential
  • Humans
  • Male
  • Mouth Diseases / pathology
  • Mouth Mucosa / pathology*
  • Mouth Neoplasms / pathology
  • Neoplasm Invasiveness
  • Neoplasms, Multiple Primary*
  • Paget Disease, Extramammary / pathology*
  • Salivary Gland Neoplasms / pathology*