A novel CISD2 mutation associated with a classical Wolfram syndrome phenotype alters Ca2+ homeostasis and ER-mitochondria interactions

Affiliations

• ¹ Université Côte d'Azur, CHU, Inserm, CNRS, IRCAN, France.
• ² Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, International Centre for Life, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK.
• ³ Fédération de Neurologie, Université Pierre et Marie Curie et Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
• ⁴ Joint Centre for Applied Electron Microscopy, Nice Sophia-Antipolis University, Nice, France.
• ⁵ UMR7592 CNRS, Jacques Monod Institute, Paris Diderot University, Paris, France.
• ⁶ UMR 7622 CNRS et UPMC et Fédération de Neurologie, Université Pierre et Marie Curie et Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
• ⁷ Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
• ⁸ NIHR Biomedical Research Centre at Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, UK.