Inferring Human Demographic Histories of Non-African Populations from Patterns of Allele Sharing

Jeffrey D Wall

doi:10.1016/j.ajhg.2017.04.002

Inferring Human Demographic Histories of Non-African Populations from Patterns of Allele Sharing

Am J Hum Genet. 2017 May 4;100(5):766-772. doi: 10.1016/j.ajhg.2017.04.002.

Author

Jeffrey D Wall¹

Affiliation

¹ Institute for Human Genetics, University of California San Francisco, San Francisco, CA 94143, USA. Electronic address: jeff.wall@ucsf.edu.

Abstract

Recent human-genetics studies have come to different conclusions regarding how and when modern humans spread out of Africa and into the rest of the world. I present here a simple parsimony-based analysis that suggests that East Asians and Melanesians are sister groups, and I discuss what implications this has for recent claims made about the demographic histories of non-African populations.

MeSH terms

Alleles*
Asian People / genetics*
Computer Simulation
Databases, Genetic
Demography*
Gene Frequency
Genetics, Population*
Genome, Human
Humans
Melanesia
Models, Biological
Polymorphism, Single Nucleotide