The Effects of Insomnia and Sleep Loss on Cardiovascular Disease

Sleep Med Clin. 2017 Jun;12(2):167-177. doi: 10.1016/j.jsmc.2017.01.005. Epub 2017 Mar 25.


Sleep loss has negative impacts on quality of life, mood, cognitive function, and heath. Insomnia is linked to poor mood, increased use of health care resources, decreased quality of life, and possibly cardiovascular risk factors and disease. Studies have shown increase in cortisol levels, decreased immunity, and increased markers of sympathetic activity in sleep-deprived healthy subjects and those with chronic insomnia. The literature shows subjective complaints consistent with chronic insomnia and shortened sleep can be associated with development of diabetes, hypertension, and cardiovascular disease. This article explores the relationship between insufficient sleep and insomnia with these health conditions.

Keywords: Cardiovascular disease; Diabetes; Hypertension; Insomnia; Prediabetes; Short sleep duration.

Publication types

  • Review

MeSH terms

  • Affect
  • Cardiovascular Diseases / epidemiology*
  • Cognition
  • Diabetes Mellitus / epidemiology
  • Humans
  • Hypertension / epidemiology
  • Quality of Life
  • Risk Factors
  • Sleep Deprivation / physiopathology
  • Sleep Initiation and Maintenance Disorders / complications*
  • Sleep*