Most Alternative Isoforms Are Not Functionally Important

Trends Biochem Sci. 2017 Jun;42(6):408-410. doi: 10.1016/j.tibs.2017.04.002. Epub 2017 May 5.

Authors

Michael L Tress¹, Federico Abascal², Alfonso Valencia³

Affiliations

¹ Department of Structural and Computational Biology, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain. Electronic address: mtress@cnio.es.
² Wellcome Trust Sanger Institute, Hinxton, UK.
³ Current address: Life Sciences Department, Barcelona Supercomputing Center (BSC-CNS), 08034 Barcelona, Spain.

No abstract available

Keywords: alternative splicing; biological complexity; mass spectrometry; selection.

Publication types

Letter
Comment

MeSH terms

Alternative Splicing*
Humans
Protein Isoforms / genetics*

Substances

Protein Isoforms

Grant support

U41 HG007234/HG/NHGRI NIH HHS/United States