Introduction: Immunology and Assisted Reproductive Technology in the 21st Century

Fertil Steril. 2017 Jun;107(6):1267-1268. doi: 10.1016/j.fertnstert.2017.04.017. Epub 2017 May 5.


In the past few years we have witnessed reproductive immunology taking a leading role after repeated implantation failure. We still face the problem of even euploid embryos that either fail to implant or are miscarried. These focused articles present the attending clinician with the most recent evidence to understand how immunology contributes to human reproduction, what can be done at the clinical level, and what is still an area for research and should not be offered to patients outside of a clinical research scenario.

Keywords: HLA; IVF; Implantation failure; KIR; NK cells.

Publication types

  • Review

MeSH terms

  • Allergy and Immunology / trends*
  • Embryo Implantation / immunology*
  • Female
  • Humans
  • Immunotherapy / trends*
  • Infertility, Female / immunology*
  • Infertility, Female / therapy*
  • Models, Immunological
  • Pregnancy
  • Reproductive Techniques, Assisted / trends*