Die randunscharfe Papille: eine diagnostische Herausforderung

Klin Monbl Augenheilkd. 2017 Jun;234(6):829-850. doi: 10.1055/s-0043-108489. Epub 2017 May 9.
[Article in German]


Correct differential diagnosis in cases of blurred optic disc margins is a challenging task for ophthalmologists. The reliable differentiation of pseudopapilloedema and true papilloedema has significant implications for proper patient management. Conditions that give rise to pseudopapilloedema include small crowded discs, tilted discs and optic nerve head drusen. Conditions that cause bilateral true swelling of the optic nerve head with initially good visual acuity include those that are secondary to raised intracranial pressure (optic disc edema, ODE). The majority of cases, however, present with unilateral optic nerve head swelling and normal intracranial pressure. They have systemic signs or symptoms which either precede ocular manifestation or have ophthalmoscopic signs other than elevation of the optic disc pointing to its diagnosis. Ancillary testing has been utilized to aid in identification of true ODE or swelling, including ultrasonography, fluorescein angiography, cranial and orbital MRI with venography, and lumbar puncture. Optical coherence tomography is also evolving as a modality for differentiation of buried optic disc drusen from ODE. This presentation will discuss each modality, with examples, advantages, and disadvantages for each.

Die Differenzialdiagnosen bei Papillenrandunschärfe sind zahlreich. Harmlose Ursachen und Normvarianten müssen von pathologischen Ursachen abgegrenzt werden. Die Papillenschwellung und insbesondere die Stauungspapille erfordern zeitnah weitere Diagnostik und Therapie.

Publication types

  • Review

MeSH terms

  • Diagnosis, Differential
  • Evidence-Based Medicine
  • Fluorescein Angiography / methods*
  • Humans
  • Magnetic Resonance Angiography / methods
  • Ophthalmoscopy / methods*
  • Optic Disk Drusen / diagnostic imaging*
  • Optic Disk Drusen / pathology*
  • Papilledema / diagnostic imaging*
  • Papilledema / pathology*
  • Tomography, Optical Coherence / methods*