An evolutionary case for functional gene body methylation in plants and animals

Genome Biol. 2017 May 9;18(1):87. doi: 10.1186/s13059-017-1230-2.


Methylation in the bodies of active genes is common in animals and vascular plants. Evolutionary patterns indicate homeostatic functions for this type of methylation.

Publication types

  • Review
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • DNA Methylation*
  • Evolution, Molecular*
  • Genes, Essential
  • Genes, Plant
  • Plants / genetics