AF and Venous Thromboembolism - Pathophysiology, Risk Assessment and CHADS-VASc score

J Atr Fibrillation. 2012 Oct 6;5(3):649. doi: 10.4022/jafib.649. eCollection 2012 Oct-Nov.


Atrial fibrillation (AF) and venous thromboembolism (VTE) are the two most common medical conditions managed with anti-coagulation therapy. Not all the patients with decreased mobility or AF have a similar risk for thromboembolism. The risk factors for venous thromboembolism and thromboembolism associated with AF are described in various studies. Considering that the two conditions have similar pathophysiologic basis of clot formation, one could imply that the risk factors for the occurrence of thrombosis could be similar. The present review focuses on the similarities and differences in the clinical risk factors of VTE and AF related thromboembolism. We will also be discussing the role of CHADS2-VASc scoring system in the risk assessment of VTE.

Publication types

  • Review