Keratitis by a rare pathogen Colletotrichum gloeosporioides: A case report

J Mycol Med. 2017 Sep;27(3):407-411. doi: 10.1016/j.mycmed.2017.04.009. Epub 2017 May 10.

Abstract

Colletotrichum species have been reported infrequently as the cause of keratitis or subcutaneous lesions. The patient we describe developed keratitis after ocular trauma. The sample from the corneal scrapings grew Colletotrichum gloeosporioides as identified from morphological characters and DNA sequence of the 'Internal Transcribed Spacer' (ITS) region. The patient underwent topical application of amphotericin-B followed by itraconazole and natamycin treatment. Simultaneous oral voriconazole regimen leads to complete regression of corneal ulcer. This report highlights the fact that early and accurate identification and therapy can resolve keratitis caused by rare pathogen C. gloeosporioides.

Keywords: Colletotrichum gloeosporioides; Internal transcribed spacer sequence; Keratitis.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use
  • Colletotrichum / isolation & purification*
  • Corneal Ulcer / drug therapy
  • Corneal Ulcer / microbiology
  • Eye Infections, Fungal / drug therapy
  • Eye Infections, Fungal / microbiology*
  • Eye Infections, Fungal / pathology
  • Humans
  • Keratitis / drug therapy
  • Keratitis / microbiology*
  • Keratitis / pathology
  • Male
  • Middle Aged
  • Voriconazole / therapeutic use

Substances

  • Antifungal Agents
  • Voriconazole