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. 2017 Jun;64(3):487-505.
doi: 10.1016/j.pcl.2017.01.003.

Gastroesophageal Reflux Disease

Free PMC article

Gastroesophageal Reflux Disease

Hayat Mousa et al. Pediatr Clin North Am. .
Free PMC article


Gastroesophageal reflux (GER) is a normal physiologic process. It is important to distinguish GER from GER disease (GERD) since GER does not require treatment. Although a diagnosis of GERD can largely be based on history and physical alone, endoscopy and pH impedance studies can help make the diagnosis when there in atypical presentation. In children and adolescents, lifestyle changes and acid suppression are first-line treatments for GERD. In infants, acid suppression is not effective, but a trial of hydrolyzed formula can be considered, as milk protein sensitivity can be difficult to differentiate from GER symptoms.

Keywords: Endoscopy; Extraesophageal symptoms; Gastroesophageal reflux; Impedance; Lifestyle changes; Pediatrics; Proton pump inhibitors.

Conflict of interest statement

Disclosure Statement

The authors have no commercial or financial conflicts of interest or any funding sources to disclose.

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