Since 1990 The Spanish Society of Cardiology Working Group on Cardiac Catheterization and Interventional Cardiology has presented a yearly report on the data collected in the National Registry, with online support since 2010. The Steering Committee has analysed all data provided voluntarily by institutions, which consisted of a total of anywhere between 105 and 113 hospitals. Medical care was provided to a population of 46.8 million inhabitants in 2015. During this period, diagnostic procedures increased progressively from 2010, reaching a maximum of 145,836 in 2015, 86% (125,484) corresponding to coronary angiograms. This means a ratio of 3,127 diagnostic studies per million inhabitants and 2,746 coronary angiograms per million inhabitants. Total percutaneous coronary interventions have increased to 67,671 procedures, with a ratio of 1,466 per million inhabitants where 18,418 were carried out during the acute phase of myocardial infarction (21.7%). Radial access has been successfully implemented in up to 73.8% of diagnostic procedures and 76.1% of percutaneous interventions. Concerning structural interventions such as septal defects, valve interventions and closure of left atrial appendage, these have had a marked evolution over time, with a total of 1,586 TAVI and 334 LAA closure procedures performed in 2015.