Unsedated In-office Transgastrostomy Esophagoscopy to Monitor Therapy in Pediatric Esophageal Disease

J Pediatr Gastroenterol Nutr. 2018 Jan;66(1):33-36. doi: 10.1097/MPG.0000000000001631.


Monitoring therapy in esophageal inflammatory disorders such as eosinophilic esophagitis and reflux esophagitis often requires frequent endoscopic evaluation. We recently reported the effective use of unsedated in-office transnasal esophagoscopy that significantly decreased costs and anesthetic exposure associated with pediatric esophagoscopy in eosinophilic esophagitis. Here we report a series of pediatric patients with esophagitis with gastrostomy tubes who underwent unsedated transgastrostomy esophagoscopy (TGE) in an office setting. Nine patients (ages 16 months-21 years) tolerated TGE without significant adverse events. Biopsy specimens were adequate for evaluation. This series confirms that unsedated in-office TGE can be used to successfully obtain mucosal biopsies to monitor esophageal inflammatory conditions in children without the use of sedation.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Ambulatory Care / methods*
  • Child
  • Child, Preschool
  • Eosinophilic Esophagitis / diagnostic imaging*
  • Eosinophilic Esophagitis / pathology
  • Eosinophilic Esophagitis / surgery
  • Esophageal Mucosa / diagnostic imaging*
  • Esophageal Mucosa / pathology
  • Esophagoscopy / methods*
  • Female
  • Gastrostomy*
  • Humans
  • Infant
  • Male
  • Outcome Assessment, Health Care
  • Retrospective Studies
  • Young Adult