Morbidity of central compartment clearance: Comparison of lesser versus complete clearance in patients with thyroid cancer

J Cancer Res Ther. 2017 Jan-Mar;13(1):102-106. doi: 10.4103/0973-1482.199378.

Abstract

Background: Extent of central compartment neck dissection (CCND) in thyroid cancers has been a debate because of associated morbidity. There have been attempts to reduce the extent of surgery in an attempt to decrease morbidity.

Patients and methods: We analyzed the morbidity of CCND from our prospectively maintained surgical morbidity database. CCND was divided into bilateral complete clearance (BCC) and less than complete clearance (LCC). LCC was performed for clinicoradiologically node negative patients. Rates of hypocalcemia and recurrent laryngeal nerve (RLN) palsy rates were compared for LCC versus BCC. We also classified procedures performed in the central neck according to the extent of dissection.

Results: Of 153 evaluable patients, BCC was performed in 43.8% and LCC in 56.2%. Rate of postoperative hypocalcemia was 40.2% in BCC group versus 17.4% in LCC group. We had an overall RLN palsy rate of 7.4%. There was no significant difference in RLN palsy rates between the groups.

Conclusion: Lesser extent of dissection in central compartment reduces postoperative hypocalcemia but has no influence on RLN palsy rates.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Hypocalcemia / physiopathology*
  • Male
  • Middle Aged
  • Morbidity
  • Neck Dissection / adverse effects*
  • Neoplasm Staging
  • Parathyroid Glands / physiopathology
  • Postoperative Complications / physiopathology
  • Surgical Clearance / methods
  • Thyroid Neoplasms / physiopathology
  • Thyroid Neoplasms / surgery*
  • Vocal Cord Paralysis / physiopathology*