Free and total plasma concentrations of elvitegravir/cobicistat during pregnancy and postpartum: a case report

Br J Clin Pharmacol. 2017 Dec;83(12):2835-2838. doi: 10.1111/bcp.13310. Epub 2017 May 16.

¹ Division of Infectious Diseases and Hospital Epidemiology, Departments of Medicine and Clinical Research, University Hospital of Basel and University of Basel, Basel, Switzerland.
² Laboratory of Clinical Pharmacology, Department of Laboratories, University Hospital of Lausanne, Lausanne, Switzerland.
³ Division of Clinical Pharmacology, Department of Laboratories, University Hospital of Lausanne, Lausanne, Switzerland.
⁴ Infectious Diseases Service, Department of Medicine, University Hospital of Lausanne, Lausanne, Switzerland.
⁵ Department 'Femme-Mère-Enfant', University Hospital of Lausanne, Lausanne, Switzerland.

No abstract available

Keywords: cobicistat; elvitegravir; free concentrations; pharmacokinetics; pregnancy; total concentrations.

Publication types

Adult
Anti-HIV Agents / blood
Anti-HIV Agents / pharmacokinetics*
Cobicistat / blood*
Cobicistat / pharmacokinetics*
Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination / blood
Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination / pharmacokinetics
Female
HIV Infections / blood*
Humans
Postpartum Period / blood*
Pregnancy
Quinolones / blood*
Quinolones / pharmacokinetics*

Anti-HIV Agents
Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination
Quinolones
elvitegravir
Cobicistat