Reversal of Autoimmune Toxicity and Loss of Tumor Response by Interleukin-17 Blockade

N Engl J Med. 2017 May 18;376(20):1989-91. doi: 10.1056/NEJMc1703047.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Antibodies, Monoclonal / therapeutic use*
  • Antibodies, Monoclonal, Humanized / adverse effects*
  • Antibodies, Monoclonal, Humanized / therapeutic use
  • Autoimmune Diseases / complications
  • Autoimmune Diseases / drug therapy
  • Colonic Neoplasms / complications
  • Colonic Neoplasms / drug therapy*
  • Crohn Disease / complications
  • Exanthema / chemically induced
  • Humans
  • Interleukin-17 / antagonists & inhibitors*
  • Male
  • Middle Aged

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Interleukin-17
  • secukinumab
  • pembrolizumab