[Quantitative and qualitative findings of hepatitis B virus-associated antigens, receptors and antibodies in the course of the acute phase of hepatitis B infection]

Z Gastroenterol. 1988 Jul;26(7):363-73.
[Article in German]

Abstract

Receptors for pHSA may be the links between HBV and hepatocytes. Therefore, we evaluated the correlation between serum binding activity for pHSA during the acute phase of hepatitis B in relation to the decrease of surface antigen concentration.

Methods: 130 sera from 22 patients with acute (HBeAg-positive) hepatitis B were obtained weekly during an average interval of 7 weeks after the onset of the disease. R-pHSA were tested by RIA in 4 titre steps (1:50, 1:500, 1:5000, 1:50,000). HBsAg was analysed quantitatively by RIA according to the standard serum of the Paul-Ehrlich-Institute.

Publication types

  • English Abstract

MeSH terms

  • Acute Disease
  • Adult
  • Female
  • Hepatitis B / immunology*
  • Hepatitis B Antibodies / analysis*
  • Hepatitis B Antigens / analysis*
  • Hepatitis B Core Antigens / analysis
  • Hepatitis B Surface Antigens / analysis
  • Hepatitis B e Antigens / analysis
  • Hepatitis B virus / immunology
  • Humans
  • Male
  • Receptors, Albumin
  • Receptors, Antigen / analysis*
  • Receptors, Cell Surface / analysis

Substances

  • Hepatitis B Antibodies
  • Hepatitis B Antigens
  • Hepatitis B Core Antigens
  • Hepatitis B Surface Antigens
  • Hepatitis B e Antigens
  • Receptors, Albumin
  • Receptors, Antigen
  • Receptors, Cell Surface
  • hepatitis B surface antigen receptor