Abstract
Receptors for pHSA may be the links between HBV and hepatocytes. Therefore, we evaluated the correlation between serum binding activity for pHSA during the acute phase of hepatitis B in relation to the decrease of surface antigen concentration.
Methods:
130 sera from 22 patients with acute (HBeAg-positive) hepatitis B were obtained weekly during an average interval of 7 weeks after the onset of the disease. R-pHSA were tested by RIA in 4 titre steps (1:50, 1:500, 1:5000, 1:50,000). HBsAg was analysed quantitatively by RIA according to the standard serum of the Paul-Ehrlich-Institute.
MeSH terms
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Acute Disease
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Adult
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Female
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Hepatitis B / immunology*
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Hepatitis B Antibodies / analysis*
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Hepatitis B Antigens / analysis*
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Hepatitis B Core Antigens / analysis
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Hepatitis B Surface Antigens / analysis
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Hepatitis B e Antigens / analysis
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Hepatitis B virus / immunology
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Humans
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Male
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Receptors, Albumin
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Receptors, Antigen / analysis*
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Receptors, Cell Surface / analysis
Substances
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Hepatitis B Antibodies
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Hepatitis B Antigens
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Hepatitis B Core Antigens
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Hepatitis B Surface Antigens
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Hepatitis B e Antigens
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Receptors, Albumin
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Receptors, Antigen
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Receptors, Cell Surface
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hepatitis B surface antigen receptor