Composite examinations of 116 persons, employees of Phosphate Fertilizers Plant in Gdańsk, with an average length of service ca. 15 years, were carried out. It was found that the frequency of occurrence of the chronic non-specific diseases of the lungs was not higher than in other works where dust and gaseous hazards of respiratory tract occur. However, at persons with longer length of service, the long-term effects of fluorine influence were found. They were revealed in disturbances of the carbohydrates balance and mineral balance, with radiographically seen thickening of the osseous structure.