CT-based Techniques for Brain Perfusion

Top Magn Reson Imaging. 2017 Jun;26(3):113-119. doi: 10.1097/RMR.0000000000000129.


Recent rapid advances in endovascular treatment for acute ischemic stroke highlight the crucial role of neuroimaging especially multimodal computed tomography (CT) including CT perfusion in stroke triage and management decisions. With an increasing focus on changes in cerebral physiology along with time-based matrices in clinical decisions for acute ischemic stroke, CT perfusion provides a rapid and practical modality for assessment and identification of salvageable tissue at risk and infarct core and provides a better understanding of the changes in cerebral physiology. Although there are challenges with the lack of standardization and accuracy of quantitative assessment, CT perfusion is evolving as a cornerstone for imaging-based strategies in the rapid management of acute ischemic stroke.

Publication types

  • Review

MeSH terms

  • Brain Ischemia / diagnostic imaging*
  • Endovascular Procedures / methods*
  • Humans
  • Multimodal Imaging / methods
  • Neuroimaging / methods*
  • Perfusion
  • Randomized Controlled Trials as Topic
  • Stroke / diagnostic imaging*
  • Tomography, X-Ray Computed / methods