Rat mPFC and M2 Play a Waiting Game (at Different Timescales)

Angela J Langdon; Andrew M Wikenheiser; Geoffrey Schoenbaum

doi:10.1016/j.neuron.2017.05.006

Rat mPFC and M2 Play a Waiting Game (at Different Timescales)

Neuron. 2017 May 17;94(4):700-702. doi: 10.1016/j.neuron.2017.05.006.

Authors

Angela J Langdon¹, Andrew M Wikenheiser², Geoffrey Schoenbaum³

Affiliations

¹ Princeton Neuroscience Institute, Princeton University, Princeton, NJ, 08544, USA. Electronic address: alangdon@princeton.edu.
² National Institute on Drug Abuse, Baltimore, MD, 21224, USA.
³ National Institute on Drug Abuse, Baltimore, MD, 21224, USA. Electronic address: geoffrey.schoenbaum@nih.gov.

PMID: 28521123
DOI: 10.1016/j.neuron.2017.05.006

Abstract

In this issue of Neuron, Murakami et al. (2017) relate neural activity in frontal cortex to stochastic and deterministic components of waiting behavior in rats; they find that mPFC biases waiting time, while M2 is ultimately responsible for trial-to-trial variability in decisions about how long to wait.

Published by Elsevier Inc.

MeSH terms

Animals
Frontal Lobe*
Neurons
Prefrontal Cortex*
Rats