Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 May;38(Suppl 1):201-206.
doi: 10.1007/s10072-017-2916-7.

Transcutaneous Supraorbital Neurostimulation for the Prevention of Chronic Migraine: A Prospective, Open-Label Preliminary Trial

Affiliations

Transcutaneous Supraorbital Neurostimulation for the Prevention of Chronic Migraine: A Prospective, Open-Label Preliminary Trial

Paola Di Fiore et al. Neurol Sci. .

Abstract

Since chronic migraine is difficult to treat and often associated with medication overuse, non-invasive neurostimulation approaches are worth investigating. Transcutaneous supraorbital neurostimulation using the Cefaly® device is promising as a non-invasive preventive treatment for episodic migraine, but no data are available for chronic migraine. Our aim was to perform a preliminary evaluation of the efficacy of the Cefaly® device for the prophylaxis of chronic migraine with or without medication overuse. Primary endpoints were 50% reduction in monthly migraine days and 50% reduction in monthly medication use over 4 months. In an open-label study, twenty-three consecutive headache center patients with chronic migraine, diagnosed according to International Headache Society criteria, were recruited prospectively. After informed consent, patients were trained to use Cefaly® and instructed to use it for 20 min daily over 4 months. All patients received active neurostimulation. Thirty-five percent of the patients enrolled in the study achieved the study endpoints. Over half the patients had a greater than 50% reduction in acute medication consumption.

Keywords: Chronic migraine; Medication overuse; Migraine prophylaxis; Transcutaneous supraorbital neurostimulation.

Similar articles

See all similar articles

Cited by 6 articles

See all "Cited by" articles

References

    1. Neurol Sci. 2010 Jun;31 Suppl 1:S23-8 - PubMed
    1. Cephalalgia. 2003 Oct;23(8):820-4 - PubMed
    1. Headache. 2009 Jul;49(7):983-9 - PubMed
    1. Neurology. 2003 Jul 22;61(2):160-4 - PubMed
    1. Cephalalgia. 2010 Jul;30(7):793-803 - PubMed

LinkOut - more resources

Feedback