Role of NOX2 for leukaemic expansion in a murine model of BCR-ABL1 + leukaemia

Br J Haematol. 2018 Jul;182(2):290-294. doi: 10.1111/bjh.14772. Epub 2017 May 23.
No abstract available

Keywords: BCR-ABL1; NADPH oxidase; NOX2; chronic myeloid leukaemia; reactive oxygen species.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bone Marrow Cells / metabolism
  • Cell Transformation, Neoplastic / pathology
  • Disease Models, Animal
  • Fusion Proteins, bcr-abl / metabolism
  • Gene Knockdown Techniques
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology*
  • Mice, Inbred C57BL
  • NADPH Oxidase 2 / deficiency
  • NADPH Oxidase 2 / physiology*
  • Neoplasm Transplantation
  • Survival Analysis

Substances

  • Cybb protein, mouse
  • NADPH Oxidase 2
  • Fusion Proteins, bcr-abl