Diabetes and cardiometabolic risk factors in Cambodia: Results from two screening studies

J Diabetes. 2018 Feb;10(2):148-157. doi: 10.1111/1753-0407.12570. Epub 2017 Jul 14.

Abstract

Background: Despite growing attention to diabetes throughout Asia, data from Southeast Asia are limited. This article reports rates of diabetes, hypertension, and obesity in Cambodia.

Methods: Two studies were conducted across different regions of Cambodia: (i) a 2012 screening study across urban, semi-urban, and rural areas that used point-of-care capillary glucose for determination of diabetes (n = 13 997); and (ii) a 2005 epidemiological study with random selection from two main urban areas that used oral glucose tolerance tests for determination of diabetes (n = 1863). Blood pressure and anthropometrics were also measured.

Results: In the screening study, rates of diabetes were significantly higher in urban than rural sites, with intermediate rates in semi-urban areas. There was a significant dose-response effect for urbanicity on overweight, obesity, and waist:hip ratio, with higher rates for urban versus semi-urban and for semi-urban versus rural locales. Rural sites had the lowest rates of hypertension, followed by urban and semi-urban sites. Among people who screened positive for diabetes, there was a dose-response effect for urbanicity on undiagnosed diabetes; rates of previously undiagnosed diabetes were lowest in urban (51%), followed by semi-urban (55%) and rural (67%) locales. Rural participants reported the highest rates of smoking and alcohol use. In the urban epidemiological study, prevalence rates of diabetes and impaired glucose tolerance were approximately 10%, indicating a prevalence of total glucose intolerance of approximately 20%.

Conclusions: In Cambodia, diabetes rates are high among urban residents and undiagnosed diabetes is highest among rural residents. A country-wide public health response is urgently needed; as development continues, rates of diabetes are expected to rise.

Keywords: Cambodia; comorbidities; urban; 合并症; 城市; 柬埔寨.

MeSH terms

  • Adult
  • Aged
  • Biomarkers / analysis
  • Blood Glucose / analysis
  • Body Mass Index
  • Cambodia / epidemiology
  • Cardiovascular Diseases / epidemiology*
  • Cardiovascular Diseases / etiology
  • Cardiovascular Diseases / pathology
  • Diabetes Mellitus / epidemiology*
  • Diabetes Mellitus / etiology
  • Diabetes Mellitus / pathology
  • Female
  • Follow-Up Studies
  • Glucose Tolerance Test
  • Glycated Hemoglobin / analysis
  • Humans
  • Hypertension / complications*
  • Male
  • Metabolic Diseases / epidemiology*
  • Metabolic Diseases / etiology
  • Metabolic Diseases / pathology
  • Middle Aged
  • Obesity / complications*
  • Prevalence
  • Prognosis
  • Risk Factors
  • Rural Population / statistics & numerical data*
  • Urban Population / statistics & numerical data*

Substances

  • Biomarkers
  • Blood Glucose
  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human