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. 2017 May 31;19(6):589-591.
doi: 10.1038/ncb3540.

Mitochondria Link Metabolism and Epigenetics in Haematopoiesis

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Mitochondria Link Metabolism and Epigenetics in Haematopoiesis

John C Schell et al. Nat Cell Biol. .

Abstract

Due to their varied metabolic and signalling roles, mitochondria are important in mediating cell behaviour. By altering mitochondrial function, two studies now identify metabolite-induced epigenetic changes that have profound effects on haematopoietic stem cell fate and function.

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