Delayed Umbilical Cord Clamping at <32 Weeks' Gestation: Implementation and Outcomes

Am J Perinatol. 2017 Sep;34(11):1048-1053. doi: 10.1055/s-0037-1603591. Epub 2017 May 25.

Abstract

Objectives: This study aims to evaluate the implementation of a delayed umbilical cord clamping (DCC) protocol for neonates <32 weeks. Secondarily, to evaluate the impact of DCC on maternal outcomes and on the ability to obtain umbilical cord blood gases.

Study Design: Retrospective cohort study from November 2014 to March 2016 of patients delivered by 316/7 weeks. In 2014, an institutional protocol for DCC at <32 weeks was implemented. We assessed adherence to the protocol and compared adverse maternal outcomes (utilizing a hemorrhage composite). We evaluated the impact of DCC on the ability to obtain adequate umbilical cord blood gas specimens.

Results: Of the 185 patients included in the study, 90 underwent DCC, and 72% of potentially eligible patients appropriately received DCC. There was no significant difference in the maternal hemorrhage composite outcome between DCC and immediate cord clamping (23.3 vs. 36.8%, adjusted odds ratio = 0.64, 95% confidence interval = 0.33, 1.26). There was also no significant difference in the ability to obtain a single or paired umbilical cord blood gas result.

Conclusion: Implementation of a DCC protocol for preterm neonates is feasible and was successful. We did not find an increase in maternal risk or a decrease in the ability to obtain umbilical cord blood gases following DCC.

MeSH terms

  • Apgar Score
  • Blood Gas Analysis
  • Constriction*
  • Female
  • Gestational Age
  • Hematocrit
  • Humans
  • Infant, Newborn
  • Infant, Premature*
  • Retrospective Studies
  • Time Factors
  • Umbilical Cord*